Unit 5: Physiological Structure and Life processes

 

Unit 5: Physiological Structure and Life processes



Multiple choice questions:      [1 mark each]

1.      The percentage of blood corpuscles in human blood is ……………….

a) 55%                         b) 45%                         c) 91%                         d) 65%

2.      What is the average quantity of blood in human body??

a)      5.8 liter                  b) 4.8 liter                    c) 5 liter                       d) 5.5 liter      

3.      What is the average life span of RBC?

a) 60 days                    b) 90 days                   c) 100 days                  d) 120 days

4.      Which of the disease is caused by the lack of haemoglobin or RBC in blood?

a) anaemia                   b) Leukemia                c) Leucopenia              d) Haemophilia

5.      What is the range of diameter of WBC?

a) 10-15μ                     b) 15-20 μ                   c) 8-15 μ                      d) 12-20 μ

6.      What is the average diameter of platelet?

a) 1.5 μ                                    b) 2.5 μ                                    c) 3.5 μ                                    d) 4.5 μ

7.      What is the average weight of heart in adult?

a) 300 gm                    b) 400 gm                    c) 450 gm                    d) 500 gm

8.      Which instrument is used to measure the blood pressure?

a) pressure gauge         b) manometer              c) barometer                d) sphygmomanometer

9.      Which blood group is consider as universal donor?

a) A                             b) B                             c) O                             d) AB

10.  Which blood group is called universal receptor?

a) A                             b) B                             c) O                             d) AB

11.  Which blood group has both antigen A and B?

a) A                             b) B                             c) O                             d) AB

12.  Which blood group does not have any antigen?

13.  a) A                             b) B                             c) O                             d) AB

14.  Which of the following is/are used to diagnosis of heart attack?

15.  a) ECG                                    b) MRI                                    c) Angiography                       d) all of these

16.   

Answer: 1(b), 2(d), 3(a), 4(c), 4(d), 5(c), 6(b), 7(a), 8(d), 9(c), 10(d), 11(d), 12(c)

 

Very short questions:             [1 mark each]

1.      What is life process?

Life process is the sum of all the physiological and metabolic activities carried out by living beings to survive and continue their life is called life process.

2.      What is blood circulatory system?

The blood circulatory system the system of the human body for the transportation of blood, hormones, nutrients to the different parts of human body and waste materials like uric acid, water to the respective excretory organs.

3.      Name the organs involved in blood circulatory system.

The organs involved in blood circulatory system are: heart, blood, blood vessels.

4.      What is the range of pH value of healthy human blood?

The range of pH value of a healthy human blood is 7.35-7.45.

5.      What is blood?

Blood is a red coloured thick viscous complex connective fluid made up of plasma and blood corpuscles.

6.      What is plasma?

Plasma is a transparent clear yellowish fluid of blood in which blood cells are suspended.

7.      What are the components of blood plasma?

The components of blood plasma are water (90%), protein (8%), and 2% other dissolved materials.

8.      What is RBC or erythrocytes?

RBC or erythrocytes are red coloured biconcave and enucleated structure suspended in blood plasma.

9.      Name the disease caused due to the lack of haemoglobin.

The name of the disease caused due to the lack of haemoglobin is anaemia.

10.  Name the types of leucocytes.

The types of leucocytes are granulocytes (Neutrophils, Eosinophils, Basophils) and agranulocytes (lymphocytes and monocytes)

11.  What is the average life span of WBC?

The average life span of WBC is about 15 days.

12.  What is the average number of WBC per mm3 of blood?

The average number of WBC per mm3 of blood ranges between 4,000 to 10,000.

13.  Where are WBCs destroyed?

WBCsare destroyed in live, spleen and at the site of infection.

14.  What are thrombocytes or platelets?

Thrombocytes are colourless oval or round non nucleated cytoplasmic fragments formed from giant cells of bone marrow.

15.  How many thrombocytes are found in 1mm3 of blood?

The number of thrombocytes in 1mm3 of blood ranges between 2 to 4 laks.

16.  What is the life span of platelets?

The average life span of platelets is 2-3 days.

17.  What is the function of platelets?

The function of platelets is to coagulate blood.

18.  Name the protein found in platelets that coagulate blood.

The protein found in platelets that coagulate blood is thromboplastin.

19.  What is haemophilia?

Haemophilia is a disease characterized by the deficiency of fibrinogen and platelets. In this condition blood takes long time to clot at the wound or cut region.

20.  What is thrombocytosis?

Thrombocytosis is a condition in which there is high amount of platelets in the blood that may lead to brain hemorrhage or heart attack.

21.  Name the valves present in the heart.

The valves present in the heart are: tricuspid vale, bicuspid valve, aortic valve and pulmonic valve.

22.  Where is tricuspid valve located?

Tricuspid valve is located between right auricle and right ventricle.

23.  Name the valve located between left auricle and left ventricle.

The valve present between left auricle and left ventricle is bicuspid valve or mitral valve.

24.  Name the muscular wall that separates left and right part of the heart.

The muscular wall that separates left and right part of the heart is septum.

25.  What are blood vessels?

Blood vessels are tubular muscular structure through which bold flows.

26.  Name the blood vessels present in human body.

The blood vessels present in human body are: arteries, veins and capillaries.

27.  What are arteries?

Arteries are thick walled blood vessels that carry oxygenated blood to different parts of body except pulmonary artery.

28.  The arteries do not collapse even after the death of a person, why?

Arteries are deeply seated and they are thick walled made up0 of three layers. They are elastic in nature. So, they do not collapse even after the death of a person.

29.  Write the function of bicuspid valve.

The function of bicuspid valve regulates the flow of blood from left auricle to the left ventricle and prevents back flow of blood.

30.  What is the function of pulmonic or semi-lunar valve?

The function of pulmonic valve prevents the back flow of blood from pulmonary artery.

31.  What are capillaries?

Capillaries are microscopic, extremely narrow and thin walled blood vessels for the exchange of gases, nutrients and waste materials.

32.  Write the function of capillaries.

The functions of capillaries are to exchange of various materials like oxygen, carbon dioxide, digested food, waste materials between the blood and the body tissues.

33.  What do you mean by systemic circulation?

The circulation of blood from the different parts of the body  9except lungs) to the heart is called systemic circulation.

34.  Define pulmonary circulation.

The circulation of the blood between the heart and the lungs through pulmonary vein and pulmonary artery is called systemic circulation.

35.  Define heartbeat.

The rhythmic contraction and relaxation of heart muscles is called heartbeat.

36.  What is the heart beat rate of an adult?

The heart beat rate of an adult healthy person is 60-72 times/minute.

37.  What do you mean by pulse rate?

Pulse rate is the number of times the artery expands per minute due to the blood pressure of the blood given due to the contraction of ventricles.

38.  What is blood pressure?

The pressure exerted by the flow of blood on the walls of arteries during the expansion and relaxation of the ventricles of heart.

39.  Define systolic pressure and diastolic pressure?

The pressure of blood on the walls of arteries when the ventricle contracts is called systolic pressure and the pressure of blood on the walls of arteries when the ventricle relaxed is called diastolic pressure.

40.  What is the range of systolic pressure in a healthy person?

The range of systolic pressure in a healthy person is 90 to 130 mm of Hg.

41.  What is the range ofdiastolic pressure in a healthy person?

The range of diastolic pressure in a healthy person is 60 to 80 mm of Hg.

42.  Define blood group.

The categorization of blood into different groups on the basis of presence or absence antibodies and antigens is blood group.

43.  What are antibodies?

Antibodies or aggulutinin are the protein present in blood plasma produced by the immunity system that binds to the foreign invaders like bacteria and destroy them.

44.  What are antigens?

Antigens or agglutinogen are the special protein molecules present on the surface of RBC which detect unwanted foreign cells present in the blood.

45.  Name the blood groups of human blood.

The blood groups of human blood are A, B, AB and O.

46.  What is the basis of blood group?

The basis of blood group is determined by the presence or absence of specific proteins and sugars on the surface of red blood cells, which are called antigens.

47.  What do you mean by Rh-factor?

Rh factor is a type of protein that is present on the surface of red blood cells in most people.

48.  What is high blood pressure or hypertension?

Hypertension or High blood pressure is a condition when the systolic blood pressure exceeds more than 140 mm of Hg.

49.  What is diabetes or diabetes mellitus?

Diabetes is a disease which is caused due to the increase in sugar level in the blood.

50.  Name the hormone that controls sugar level in the blood.

Insulin is the hormone that controls sugar level in the blood.

51.  Name the gland that secretes insulin.

The gland that secretes insulin is pancreas.

52.  Name the unit in which sugar level is measured.

Sugar level in blood is measured in terms mg/dL. (milligram per deciliter) [1mg =1/1000 gm, 1dL=1/100 L]

53.  What is the pre-prandial level of sugar in a healthy person?

The pre-prandial level of sugar in a healthy person is 70-99 mg/dL.

54.  What is the post-prandial level of sugar in a healthy person?

The post-prandial level of sugar in a healthy person should be less than 140 mg/dL.

55.  What is uric acid?

Uric acid is a compound formed from the breakdown of purine present in protein containing food.

56.  What is gout?

Gout is a form of arthritis that occurs when there is an excess of uric acid in the bloodstream.

57.  What is the reference range of uric acid in blood plasma?

The reference range of uric acid in blood plasma is 3.4-7.2 mg/dL.

58.  What is heart attack or myocardial infarction?

A heart attack is a serious medical emergency in which the supply of blood to heart is suddenly blocked.

59.  What is the full form of ACE inhibitor?

The full for of ACE inhibitor is Angiotensin Converting Enzyme inhibitor.

60.  What is the function of ACE inhibitor?

61.  ACE inhibitor prevents the conversion of Angiotensin I to Angiotensin II. (Angiotensin II is a potent vasco-restrictor that constrict the blood vessels.

Short questions:            [2 marks each]

1.      What are the functions of circulatory system?

a)      It transports oxygen, digested food nutrients and hormones to the various parts of body.

b)      It transports waste materials produced in different organs or tissues to the respective excretory organs.

c)      It regulates the body temperature, water, mineral content of the body.

d)     It protects our body from external pathogens and toxins.

2.      Write the properties of blood.

The properties of blood are:

i) Blood is red, viscous fluid due to the presence of haemoglobin.

ii) It is salty in taste and alkaline in nature.

iii) Its pH ranges from 7.35 to 7.45.

iv) Its specific gravity is 1.05 to 1.06.

3.      Write a short note on RBC.

RBC is a biconcave corpuscle which is red in colour due to the presence of haemoglobin. It is bounded by an elastic semi-permeable plasma membrane. It contains iron in it. Its main function is to transport oxygen in the tissues for oxidation of food. They are produced in bone marrow such as vertebrae, skull and ribs. Their life span is 120 days. On an average 1mm3 of blood possess 4.5 to 5 millions of RBC.

4.      Write two functions of RBCs.

Two functions of RBCs are:

i) They transport O2 and CO2.

ii) They balance the acid-base balance in body.

5.      What are the symptoms of anaemia?

The symptoms of anaemia are:

a) Loss in body weight.

b) Loss of appetite.

c) Slow and retarded growth.

d) Pale and dull-coloured skin.

e) Weakness and tiredness in a short walk or work.

6.      A person suffering from anaemia feels tired after a short walk?

A person suffering from anaemia has deficiency of red blood cells or haemoglobin in his/her blood. Haemoglobin are the carrier of oxygen to the body tissues and organs. So, adequate amount of oxygen cannot be supplied to the body for the respiration and to release energy. As a result, due to the lack of sufficient energy, a person feels tired after a short walk.

7.      What is leucopenia? How does it occur?

Leucopenia is a disease in which there is excessive decline in the number of WBC. It occur due to the fall in the number of neutrophils in blood when a person is subjected to chemotherapy, failure of bone marrow, disorder in immune system, low nutrition in diet and exposure to radiation. 

8.      White blood cells are called the defender of our body. Why?

White blood cells are of several types, they are considered the defender of our body because they play a critical role in our immune system. They are responsible for recognizing and attacking foreign substances, such as viruses, bacteria, and other pathogens that can cause infections and disease.

9.      What is leukemia? What are its causes?

Leukemia is a type of blood cancer which affect the blood and bone marrow due to the increase in one or more variety of leucocytes. The causes of leukemia are genetic transmission, exposure to radiation and chemicals, immunity system disorder and viral infection.

10.  Blood does not clot when inside the blood vessels but it clots outside, why?

Blood does not clot inside the blood vessels due the presence of anticoagulant called heparin or antiprothrombin. When the blood comes in contact with air, the platelets burst and produce thromboplastin which help in the production of an enzyme called prothrombinase. This enzyme inactivates heparin and converts inactive prothrombin into thrombin. So, blood does not clot inside blood vessels but it clots outside.

11.  Why is donated blood treated with sodium citrate?

Sodium citrate is an anticoagulant and does not allow the blood to clot easily. So, during the donation of the blood, sodium citrate is kept in the bag where donated blood is collected. It helps keeps the blood without clotting for the a long storage and transportation from blood bank to hospitals.

12.  The walls of left ventricle is thicker than right ventricle. Give reason.

The walls of the left ventricle are thicker than those of the right ventricle because the left ventricle pumps blood to all parts of the bodywhile the right ventricle only pumps blood to the lungs. Since the left ventricle has to pump blood more forcefully and at a higher pressure than the right ventricle, it requires more muscle to perform this function.

13.  The walls of right ventricle is thicker than the walls of right auricle, why?

The right ventricle pumps the blood into pulmonary artery forcefully with high pressure while right auricle only receives deoxygenated blood from superior and inferior vencava. So, walls of right ventricle is thicker than the auricle.

14.  Right auricle is larger than the left auricle. Give reason.

Right auricle receives deoxygenated blood from superior and inferior venacava while left auricle receives small amount of blood from the lungs through pulmonary vein. Therefore, more space is required to collect large amount of blood in the right auricle as compare to left auricle.

15.  Pulmonary artery carries deoxygenated blood, why?

Pulmonary artery carries from the right ventricle of the heart to the lungs for purification i.e. exhaling carbon dioxide and absorbing oxygen.

16.  The heart is slightly tilted towards right, why?

The right auricle of the heart receives large volume of blood from different parts of the body through superior and inferior vena cava. So, due to the presence of large volume of blood, it is slightly tilted towards right.

17.  The heart beat become faster after a long run, why?

During the long run large amount of energy is required by the body. The energy is produced by the oxidation of glucose in the cells and tissues. So, in order to supply large amount of oxygen to oxidize glucose to release energy the heart has to pump blood at the faster rate. Hence, the heart beat becomes faster after a long run.

18.  Why does the blood clot after death?

The blood clot after death due to the change of physiological and chemical factors. After death, the heart stops pumping the blood due to which its flow stops and cogulating factors accumulate at one place and hence they become active.

19.  Arteries are deeply seated while veins are superficially seated in the body, why?

Blood in the arteries flow with higher pressure in comparison to the pressure of blood in veins. So, in order withstand the high pressure of the blood they are deeply seated. In contrary, vein have very low blood pressure and it has one way valve which allows smooth flow of blood. So, arteries are deeply seated while veins are superficially seated in the body. 

20.  Bleeding from artery is more dangerous than that from veins, why?

Arteries carry oxygenated blood along with nutrients, which has very high pressure than that of veins. It is very difficult to stop bleeding due to high speed of the blood. It is quite difficult for fibrinogen and platelets to be active. Hence, excessive amount of blood is lost and the body may deprived of oxygen and energy. This may be fatal to a person. In contrast, vein carry deoxygenated blood which has very low pressure and hence there is less loss of blood from the body.

21.  Arteries have thick and elastic muscular walls, but the veins have thin walls, why?

Arteries carry oxygenated blood with very high pressure. In order to withstand the high blood pressure of the blood, the walls of arteries are thick and elastic while veins carry deoxygenated blood having low pressure and it think wall can tolerate the pressure exerted by deoxygenated blood in veins.

22.  Veins are provided with valves but the arteries do not have valves, Why?

Veins carry deoxygenated blood from the various parts which have extremely low pressure as compared to the arteries. It has to transport blood against the gravity so there is more chance of back flow of blood. Hence, to avoid the backflow of blood, veins are provided with valves. In comparison to the veins, arteries carry oxygenated blood which has extremely high pressure. Due to high speed, there is no chance of back flow of blood through arteries. Hence, they do not have valves.

23.  The people of Himalayan region have red faces, why?

The Himalayan region lies at high altitude due to which there is low atmospheric oxygen. The people living in this region are adopted to have more haemoglobin to carry large amount of oxygen in their body as compare to hilly and terai region. So, due to having large amount of haemoglobin distributed in the blood vessels throughout their body their skin appears red.

24.  Write two differences between bicuspid valve and tricuspid valve.

Two differences between bicuspid and tricuspid valve are:

Bicuspid valve or Mitral valve

Tricuspid valve

1.      It lies between left auricle and left ventricle of the heart.

1.      It lies between right auricle and right ventricle of the heart.

2.      It consists of two concentric membranous flaps.

2.      It consists of three concentric membranous flaps.

 

25.  Write the differences between pulmonary artery and pulmonary vein.

The differences between pulmonary artery and pulmonary vein are:

Pulmonary artery

Pulmonary vein

1.      They carry deoxygenated blood from right ventricle of the heart to the lungs for purification.

1.      They carry oxygenated blood from the lungs to the left auricle of the heart.

2.      It is guarded by semi-lunar valve.

2.      It is not guarded by any valve.

 

26.  Write two differences between blood cells and blood plasma.

The differences between blood cells and blood plasma are given below.

Blood Cells

Blood Plasma

1.      These are the cellular components of the blood.

1.      It is pale yellowish fluid part of the blood.

2.      They for 45% of the total volume of the blood in the body of human being.

2.      It forms 55% of the total volume of blood in the human body.

3.      They constitute RBC, WBC and platelets.

3.      It constitutes water, minerals, protein, lipids and carbohydrates.

 

27.  The blood pressure of a person is 90/130. What does it mean?

The blood pressure of a person is 90/130, it means that the systolic blood pressure of the person is 130 mm of Hg and diastolic pressure is 90 mm of Hg.

28.  Write the conditions at which heartbeat increases.

The conditions under which blood pressure increases are mentioned below:

a)      When a person runs for a long time or during hard work.

b)      During the physical exercise.

c)      During emotion, tension and fear.

d)     During illness or fever.

29.  Why is blood group O called universal donor?

Blood group O is called universal donor because it can be safely transfused to the other patient. It has neither A nor B surface antigens on the red blood cells. This is because the presence of A or B antigens on red blood cells can trigger an immune response in individuals with different blood types, leading to a potentially life-threatening reaction. This means that our immune system will not react to the blood because there is no antigen to react against. So, O blood group can be transfused in people of any blood type; hence, the term universal blood donor.

30.  Why is blood group AB called a universal receptor?

Blood group AB is called the universal recipient because individuals with this blood type have both A and B antigens on the surface of their red blood cells, which means they can receive blood from individuals with any other blood type without triggering an immune response. This is because individuals with blood group AB have developed antibodies to neither A nor B antigens, which makes it safe for them to receive blood from individuals with blood groups A, B, AB, or O.

31.  Why does a person with blood group A cannot receive blood from blood group B?

32.  A person with blood group A has red blood cells that carry the A antigen on their surface, while a person with blood group B has red blood cells that carry the B antigen on their surface.

When blood from a person with blood group B is transfused into a person with blood group A, the antibodies in the recipient's plasma (which are naturally occurring antibodies against the B antigen) recognize the B antigen as foreign and attack the transfused red blood cells, leading to a potentially life-threatening immune reaction.

33.  Write the symptoms of high blood pressure.

The symptoms of blood pressure are:

a) Headache and problem in deep breathing

b) nose bleeding

c) facial redness

d) sweating and tiredness

e ) insomnia and anxiety

34.  What are the symptoms of uric acid/gout?

The symptoms of uric acid or gout are:

a)      Joint ache and inflammation.

b)      Deep muscular pain and difficulty in walking.

c)      Redness and pain in shins.

35.  What are the causes of gout?

The causes of gout are:

a.       Kidney disorder

b.      Overweight

c.       Excessive consumption of alcohol and protein containing food.

d.      Family history of gout.

36.  Mention the treatments of heart attack.

37.  The treatments of heart attack includes the following

a)      Medication: It includes the drugs like aspirin, thrombolytic or fibrinolytic, heparin, nitroglycerin, morphin, beta blockers and ACE inhibitors

b)      Surgical procedure: It includes cardiac catheterization, Balloon angioplasty, stent placement and bypass surgery.

38.  a

Long question answer            [4 marks each]

1.      Write the functions of blood plasma.

a) Plasma transports nutrients and hormones to the different parts of the body.

b) It transports waste materials like carbon dioxide, urea, water, etc. to the respective excretory organs for excretion.

c) It maintains the body temperature, amount of water in the tissues and other metabolites.

d) Fibrinogen in blood plasma plays an important role in blood clotting.

2.       Write the  functions of white blood cells.

The functions of white blood cells include:

a)  White blood cells is to recognize and attack foreign substances, such as viruses, bacteria, and other pathogens that can cause infections and disease. They do this by engulfing and destroying these harmful substances or producing antibodies that can identify and neutralize them.

b) They also help to regulate immune responses by controlling the activity of other immune cells, such as T cells and B cells. This helps to ensure that the immune system responds appropriately to different types of threats.

c) They help to remove dead cells and debris from the body, which can help to prevent inflammation and infection.

d) They are also involved in allergic reactions, helping to identify and respond to allergens in the body.

3.      Describe the functions of blood.

i) Transportation of gases: Blood transport oxygen from the lungs to the tissues for oxidation and carbon dioxide from the tissues to the lungs for exhaling.

ii) Transport of nutrients:  The digested food materials are transported from the intestine to various parts of the body.

iii) Transportation of waste products:the waste products produced as a result of metabolism are transported to the respective excretory organs for their removal from the body.

iv) Transportation of hormones: The hormones produced by the different endocrine glands are transported to the targeted site or organs.

v) Defense against pathogens: WBC present in the blood help to prevent against disease causing germs or pathogens.

vi) Prevent the blood loss: Prothrombin and fibrinogen present in the platelets and blood plasma help in blood clotting at the wound or injured parts.

vii) Balance water and maintain temperature: Blood maintain the body temperature and water in the body tissues.

4.      Describe human heart in brief with figure. Or Draw a well labeled diagram of human heart.

The human heart is a muscular organ that is responsible for pumping blood throughout the body. It is located in the chest cavity, between the lungs, and is roughly the size of a fist. The heart is surrounded by fluid containing a sac called the pericardium, which helps to protect and lubricate the heart. The heart has four chambers: the right auricle, right ventricle, left auricle, and left ventricle. Auricles are the upper chambers, and the ventricles are the lower chambers of the heart

The right auricle receives deoxygenated blood through superior and inferior venacava from the body, which then flows into the right ventricle. The right ventricle pumps this deoxygenated blood to the lungs for oxygenation. Oxygenated blood returns to the left auricle of the heart via pulmonary vein, and then flows into the left ventricle. The left ventricle pumps this oxygenated blood to the rest of the body through the aorta.

1.      Write the differences between RBC and WBC.

The differences between RBC and WBC are:

RBC

WBC

1.      RBC are biconcave shaped.

1.      WBC are irregular shaped.

2.      They are smaller than WBC.

2.      They are larger than WBC.

3.      They are non-nucleate.

3.      They may be nucleate.

4.      They are more in number.

4.      They are less in number.

5.      They are red in colour due to the presence of haemoglobin.

5.      They are colourless due to the lack of haemoglobin.

6.      They help in carrying oxygen.

6.      They help in defending against pathogens.

 

2.      Write the differences between arteries and veins.

The differences between arteries and veins are:

Arteies

Veins

1.      Arteries carry blood away from the heart.

1.      Veins carry blood to the heart.

2.      They are deeply seated.

2.  They are superficially seated.

1.      They do not have valves.

3.      They have valves.

2.      They are thick walled.

4.      They are thin walled.

3.      They carry oxygenated blood except pulmonary artery.

5.      They carry deoxygenated blood except pulmonary vein.

4.      They have narrow lumen.

6.      They have wide lumen.

 

3.      Write the differences between auricle and ventricle.

On the basis of location and function there are certain differences between auricle and ventricle of the heart. They are as follows:

Auricle

Ventricle

1.      Auricles are upper chamber of the heart.

1.      Ventricles are lower chambers of heart.

2.      They are thin walled.

2.      They are thick walled.

3.      They receive blood from the different parts of the body.

3.      They transmit blood to the different parts of the body.

4.      Veins arise from auricles.

4.      Arteries arise from ventricle.

 

4.      How does Rh-factor behave in the blood transfusion?

The Rh factor plays a significant role in blood transfusions. Rh factor refers to the presence or absence of a specific antigen called the RhD antigen on the surface of red blood cells.

When a person with Rh-negative blood receives a blood transfusion, it is essential to match their blood type with Rh-negative blood. If Rh-positive blood is transfused into an Rh-negative individual, it can lead to an immune response. The first exposure of an Rh-negative individual to Rh-positive blood triggers the production of antibodies against the RhD antigen. This process is known as sensitization. However, the initial immune response is usually not severe and may not cause noticeable symptoms.

In second transfusions with Rh-positive blood, or in certain other situations such as pregnancy, these preformed antibodies can quickly recognize and attack the Rh-positive red blood cells. This immune response leads to the destruction of the transfused Rh-positive cells, causing a reaction known as a transfusion reaction.

5.      A serious problem arise if an Rh-negative mother is carrying a Rh-positive foetus. Explain.

When an Rh-negative mother is carrying an Rh-positive fetus, a serious problem can arise due to a condition called Rh incompatibility or Rh sensitization. This occurs when the Rh-negative mother's immune system comes into contact with the Rh-positive blood of the fetus, leading to the production of antibodies against the Rh factor.

During the first pregnancy, there can be instances when the Rh-positive fetal blood can mix with the Rh-negative maternal blood. The first pregnancy is usually not affected by Rh incompatibility, as sensitization typically occurs during or after delivery. However, if the mother becomes sensitized during the first pregnancy, her immune system recognizes the Rh-positive blood as foreign and produces antibodies to destroy it. During the second pregnancy, if the foetus is Rh-positive then a large number of RBCs of the foetus are destroyed as antibodies of the immune system recognize Rh-negative as foreign substance and destroy large number of RBC of the foetus leading to haemolytic disease to newborn child. In this case the baby may experience jaundice, anemia, or severe swelling, organ failure, and even fetal death.

6.      Write the causes of high blood pressure.

The causes of high blood pressure are:

a)      Smoking

b)      Lack of physical exercise

c)      Too much alcohol consumption

d)     Older age and heredity cause

e)      Chronic kidney disease and thyroid disorder

f)       Having overweight or obesity

g)      Too much salt in diet

h)      Stress and sleep apnea

i)        Excessive consumption of fatty, spicy and fried foods.

j)        Lack of physical exercise.

7.      Write the preventive measure of high blood pressure.

The preventive measure of high blood pressure are:

a)      Care should be taken in food.

b)      Over eating should be avoided.

c)      Less salt should be used in food.

d)     Regular exercise should be done.

e)      Smoking and consumption of alcohol should be avoided.

f)       Stress should be avoided by developing positive thought.

g)      Blood pressure should be checked regularly and necessary precaution should be followed.

8.      What are the symptoms of diabetes?

The symptoms of diabetes are:

a)      Frequent urination (Polyuria)

b)      Passing out sugar in urine

c)      Feel excessive thirst and hunger.

d)     Delay in wound healing.

e)      Fall in body weight and dizziness.

f)       Muscles cramping.

9.      Mention the causes of diabetes.

The causes of diabetes are:

a)      Hypo-secretion of insulin hormone due to malfunctioning of pancreas.

b)      It is sometimes a genetic disease and can be transmitted from parents to offspring.

c)      Eating too much fatty and carbohydrate containing food.

d)     Overweight or obesity and lack of exercise.

e)      It may also be caused due to the lack of balance diet.

10.  Mention the preventive measure of diabetes.

The preventive measures of diabetes are as follows:

a)      Obesity should be reduced.

b)      Balance diet should be taken.

c)      Hypertension should be reduced.

d)     Physical exercise should be done regularly.

e)      Regular morning walk should be done.

f)       We should avoid smoking and drinking alcohol.

g)      Excessive consumption of carbohydrate containing food should be reduced.

h)      We should consume sufficient amount of green vegetables and fruits.

11.  Write the preventive measures of gout.

The preventive measures of gout are:

a)      Diet containing high purine like fatty food, red meat, legumes should be reduced

b)      Excessive alcohol consumption should be reduced.

c)      Overweight should be reduced.

d)     Drinking plenty of water may reduce gout or hyperuricemia.

e)      Drinking baking soda solution helps to reduce uric acid level.

f)       Use of olive oil as cooking is advantageous to reduce uric acid.

g)      Consumption of wheat grass juice also reduce uric acid.

h)      Use of lemon and other citrus fruit with hot water can also be helpful.

i)        Use of cherries as well as purple and blue berries contain anthocyanin, which lowers the uric acid.

12.  What are the causes or risk factors of heart attack?

The causes of heart attack are:

a)      Coronary heart disease

b)      Smoking

c)      Alcohol consumption

d)     Obesity

e)      Old age

f)       High fat diet consumption

g)      Diabetes

h)      High blood pressure or hypertension

i)        Lack of physical exercise

j)        Family history of heart disease.

13.  What are the signs and symptoms of heart attack?

The signs and symptoms of heart attack are as follows:

a)      Sharper chest pain at the centre or left side of the chest.

b)      Feeling discomfort in breathing.

c)      Feeling weak, light headed, cold sweat and dizziness.

d)     Pain in neck, jaws and back.

e)      Fatigue, nausea and vomiting.

14.  What are the preventive measure of heart attack?

The preventive measures of heart attack are as follows:

a)      Avoid smoking and alcohol consumption

b)      Regular exercise and physical exercise

c)      Consumption of healthy food with low sodium, fat and sugar.

d)     Stress should be control

e)      Regular test for cholesterol, blood pressure and blood sugar level

15.  Describe cardiac catheterization.

Cardiac catheterization is a medical procedure where a thin, flexible tube called a catheter is inserted into a blood vessel in the arm, groin, or neck and threaded through to the heart. This procedure is used to diagnose and treat heart conditions such as coronary artery disease, heart valve problems, and congenital heart defects.

During the procedure, the patient is given a local anesthetic to numb the area where the catheter will be inserted. The catheter is then guided through the blood vessel to the heart using X-ray imaging. Once the catheter is in place, the doctor can measure the pressure inside the heart and blood vessels, inject dye to visualize the blood flow, and perform other diagnostic tests. In some cases, cardiac catheterization can also be used to treat heart conditions. For example, a balloon catheter can be used to open blocked arteries or a stent can be placed to keep the artery open. Overall, cardiac catheterization is a useful tool for diagnosing and treating heart conditions, but like any medical procedure, it carries some risks and should only be performed when necessary.



1.      Describe balloon angioplasty.

Balloon angioplasty is a medical procedure used to treat narrowed or blocked blood vessels, typically in the heart. During the procedure, a small, flexible tube called a catheter is inserted into the affected blood vessel through a small incision. A deflated balloon is then threaded through the catheter and positioned at the site of the blockage. The balloon is then inflated, which compresses the plaque or blockage against the walls of the blood vessel, widening the vessel and improving blood flow. The balloon is then deflated and removed, and the catheter is withdrawn. The procedure is minimally invasive and is often used as an alternative to more invasive surgical procedures.

 


2.      Describe stent placement.

Stent placement is a medical procedure that involves inserting a small, mesh-like tube called a stent into a narrowed or blocked blood vessel. The stent is typically inserted using a catheter that is threaded through a small incision in the skin and into the affected blood vessel. Once the stent is in place, it is expanded using a small balloon, which compresses the plaque or blockage against the walls of the blood vessel and widens the vessel. The stent remains in place, acting as a scaffold to keep the blood vessel open and improve blood flow. Stent placement is often used to treat conditions such as coronary artery disease, peripheral artery disease, and renal artery stenosis.



3.      Describe bypass surgery.

Bypass surgery, also known as coronary artery bypass grafting (CABG), is a surgical procedure used to treat blocked or narrowed coronary arteries. During the procedure, a surgeon takes a healthy blood vessel, typically from the leg or chest, and attaches it to the blocked or narrowed coronary artery, creating a new route for blood to flow around the blockage. This new blood vessel is called a graft. The surgery is typically performed under general anesthesia and involves making an incision in the chest to access the heart. The heart is then stopped temporarily, and a heart-lung machine takes over the function of the heart and lungs during the surgery. Once the graft is in place, the heart is restarted, and the chest incision is closed. Bypass surgery is a major surgery and is typically reserved for cases where other treatments, such as medication or angioplasty, have not been successful.



4.      Study the given figure and answer the following questions.



a)      What is shown in the above diagram?

Sample of blood is shown in the diagram.

b)     Name the parts A, B, C and D.

The part A is red blood corpuscles, B is blood plasma, C is white blood cell and D is platelets.

c)      Write the function of A and C.

The function of A is to carry oxygen to the different parts of the body and the function of C is the defend against the disease germs.

d)     Name the disease caused due to the lack of D.

Haemophilia is caused due to the lack of D.

e)      Which disease is caused due to the lack of C?

Leukopenia is caused due to the lack of C.

Glossary

Circulatory system:

The system in human body related to the supply of nutrients, oxygen, hormones, etc. to the tissues and organs and carry away the waste from the tissues and organs to respective excretory organs with the help of blood.

Blood:

A thick viscous red coloured fluid connective tissue consisting of 55% blood plasma and 45% blood cells.

Plasma:

A yellowish coloured semi-transparent liquid present in the blood.

Red blood corpuscles:

Red blood cells (RBCs) are red-coloured, biconcave, enucleated structure suspended in the blood.

White blood corpuscles:

WBCs are irregular, colourless blood cells which have nucleus and other cell orgnells.

Platelets:

Platelets are non-nucleated irregular, colourless, round or oval blood cells found freely suspended in the blood plasma.

Anaemia

A condition which is caused due to the lack of RBCs or haemoglobin  in the blood.

Haemophilia:

A condition in which blood clotting delays in the cut or wound due to the absence of blood-clotting chemicals.

Leukaemia:

Leukaemia is a condition in which a person has excess of WBC in his/her body as compared to the normal limit.

Leukopenia:

A condition in which a person less number of WBC in his or her body as compared to the normal person.

Blood clotting:

The process of formation of solid mesh at the site of cut and wound.

Arteries:

Arteries are thick walled blood vessels that carry blood away from the heart.

Blood vessels:

The elastic tubes through which the blood flows.

Veins:

Thin walled blood vessels with valves that carry blood towards the heart.

Capillaries:

Capillaries are hair-like extremely narrow and thin walled blood vessels.

Pericardium:

A A double layered membranous structure that covers the heart.

Pericardial fluid:

A lubricating fluid in the pericardial cavity.

Pericardial cavity:

A gap between two layers of pericardium.

Tricuspid Valve:

A valve between right auricle and right ventricle of the heart.

Bicuspid valve:

A valve between left auricle and left ventricle of the heart.

Pulmonary valve:

A valve present between pulmonary artery and right ventricle.

Aortic valve:

A valve between aorta and left ventricle.

Blood pressure:

The pressure exerted by the blood on the walls of the arteries when the left ventricle contracts and relaxes.

Systolic blood pressure:

The measure of maximum pressure in the arteries when left ventricle contracts.

Diastolic blood pressure:

The measure of minimum pressure in the arteries when left ventricle relaxes.

High blood pressure:

A condition in which a person's blood pressure is equal to or greater than 140/90 mm of Hg.

Heart beat:

Rhythmic contraction and relaxation of heart muscles.

Arterial pulse:

The repetitive jerk felt at the major arteries of the body due to the pumping action of the heart.

Pulmonary circulation:

The type of circulation of blood in which blood flows from right ventricle to lungs.

Systemic circulation:

The type of circulation of blood in which blood flows from left ventricle to the right auricle of the heart through body tissue (except lungs).

Insulin:

A hormone secreted by pancreas that helps in maintaining glucose level in blood.

Diabetes:

The condition in which body becomes unable to maintain normal glucose level due to the lack of insulin.

Uric acid:

Uric acid is an antioxidant which help to remove toxic materials from our body and also protect the inner walls of the blood vessels.

Gout (uric acid):

Gout is a form of arthritic disease which is characterized by the deposition of uric acid crystals in the joints like knees, toes, etc. 

Heart attack:

The blockage of the flow of oxygenated blood in the cardiac tissue of the heart.

Bypass surgery:

A surgery made by passing the blood supply to the heart tissues through an alternative artery.

Angiography:

Angiography is an effective way to treat a heart attack. It uses an x-ray imaging technique to find the blood clot. After that a catherter or a tiny balloon is used to open the blockage.

Fibrinogen:

Fibrinogen is a protein produced by the liver that helps blood clots to form.

Haemoglobin:

Haemoglobin is a red coloured pigment associated with the transport of oxygen.

Septum:

A muscular margin that separates the heart into two parts viz. left and right.

Antibody:

A kind of protein found in blood plasma.

Antigen:

A kind of protein molecule found on the surface of RBC.

Auricle:

The upper chamber of the heart.

Ventricle:

The lower chamber of the heart.

Aspirin:

A medicine to relieve pain.

Angioplasty:

Angioplasty is a minimally invasive procedure that is used to widen narrowed or blocked arteries.

Sphygmomanometer:

An instrument used to measure the blood pressure.





Post a Comment

Thank you for your comment

Previous Post Next Post